ACTRN12612000181808已完成未知
Efficacy and safety study of dihydroarteminisinin-piperaquine and artemether-lumefantrine for the treatment of uncomplicated Plasmodium falciparum malaria and dihydroartemisinin-piperaquine for plasmodium vivax treatment in Ochra Health Centre (Pailin Province), Promoy Health Centre (Pursat Province), and in Veunsai Health Centre (Rattanakiri province), Cambodia 2010
ational Centre for Malaria Control0 个研究点目标入组 420 人开始时间: 2012年2月10日最近更新:
适应症
试验速览
- 阶段
- 未知
- 状态
- 已完成
- 发起方
- 入组人数
- 420
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
- 分配方式
- Non-randomised trial
- 主要目的
- Treatment
- 盲法
- Open (masking not used)
入排标准
- 年龄范围
- 2 Years 至 45 Years（—）
- 性别
- All
入选标准
- •Above 2years old (all age groups);
- •-Mono Infection with P. falciparum or P. vivax;
- •-Parasitaemia, 2000–200 000 asexual forms per microlitre ;
- •-Axillary temperature greater than 37.5 degree C
- •-Ability to swallow oral medication;
- •-Ability and willingness to comply with the study protocol for the duration of the study and to comply with the study visit schedule;
- •-Informed consent from the patient or from a parent or guardian in case of children.
排除标准
- •-Presence of general danger signs among children <5 years old or other signs of severe and complicated falciparum malaria according to current WHO definitions;
- •-Mixed Plasmodium species;
- •-Presence of febrile conditions due to diseases other than malaria (measles, acute lower tract respiratory infection, severe diarrhea with dehydration, etc.),
- •-Known hypersensitivity or allergy to artesunate or mefloquine
- •-Known psychiatric disorders, e.g. depression or epilepsy
- •-Anti arrhythmic or others drugs which are known to influence cardiac function
研究者
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