NCT01270243已完成不适用
Bacterial Microbiota In The Tonsils Of Children Undergoing Adenotonsillectomy And Normal Controls
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 24
- 试验地点
- 1
研究概览
简要总结
We, the investigators, propose to look at the bacteria on and in tonsils using gene microarrays. We expect to find previously reported bacteria but also the possibility of previously undetected organisms. We think that the bacterial pathogens present on the tonsillar surface are different from the tonsil core. And we also think that the bacteria of the tonsil surface will differ between patients undergoing adenotonsillectomy and normal controls with no adenotonsillar problems.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 年龄范围
- 2 Years 至 12 Years（Child）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Inclusion criteria for subjects undergoing surgery:
- •Age 2-12 yrs
- •Both males and females
- •Undergoing adenotonsillectomy
- •Additional criteria for subjects in the recurrent infection group:
- •Sleep questionnaire score <5
- •Designated by surgeon as having recurrent adenotonsillitis as reason for surgery
- •Additional criteria for subjects in the airway obstruction group:
- •Sleep questionnaire score >5
- •Presence of positive polysomnogram desired but not necessary
- •Designated by surgeon as having airway obstruction or sleep apnea as reason for surgery
- •Inclusion criteria for control subjects:
- •Age 2-12 yrs
- •Both males and females
- •No history of adenotonsillar problems
- •Sleep questionnaire score < 5
排除标准
- •Exclusion Criteria for both groups:
- •Antibiotic intake in the past 10 days
- •Other major medical problems (immune deficiency, cystic fibrosis, malignancy) In the surgery group: designated by surgeon as having both recurrent adenotonsillitis and airway obstruction as reason for surgery Menstruating females
研究者
研究点 (1)
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