NCT04530539已完成不适用
The Effect of Melatonin and Vitamin C on COVID-19
适应症
干预措施
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 122
- 试验地点
- 1
- 主要终点
- Symptom Severity
研究概览
简要总结
This is a double-blind placebo controlled trial that seeks to evaluate the impact of melatonin and vitamin C on symptoms and outcomes of patients with COVID-19.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Supportive Care
- 盲法
- Triple (Participant, Care Provider, Investigator)
入排标准
- 年龄范围
- 50 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •COVID-19 positive test (outpatient testing),
- •Age >50 (chosen based greater risk for older patients to be vitamin deficient, age >65 not used so as not to be too restrictive in the inclusion criteria)
- •Experiencing symptoms for <5 days prior to enrollment
- •Able to read and write in English or Spanish
- •Able to access REDCap daily
- •Valid email address
- •Current has a Lancaster General Health primary care physician
排除标准
- •COVID-19 test ordered pre-procedure for asymptomatic screening
- •Currently taking vitamin C supplements
- •Currently taking melatonin supplements
- •Currently hospitalized
- •Currently pregnant
- •Currently incarcerated
研究组 & 干预措施
Experimental- Melatonin
Experimental
Patients will receive melatonin
干预措施: Symptom Survey (Other)
Experimental- Vit C
Experimental
Patients will receive vitamin C
干预措施: Symptom Survey (Other)
Control
Placebo Comparator
Patients will receive placebo
干预措施: Placebo (Dietary Supplement)
Control
Placebo Comparator
Patients will receive placebo
干预措施: Symptom Survey (Other)
Experimental- Vit C
Experimental
Patients will receive vitamin C
干预措施: Vitamin C (Dietary Supplement)
Experimental- Melatonin
Experimental
Patients will receive melatonin
干预措施: melatonin (Dietary Supplement)
结局指标
主要结局
Symptom Severity
时间窗: 14 days
Symptom severity will be tracked electronically
次要结局
- Symptom progression(14 days)
研究者
研究点 (1)
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