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临床试验/NL-OMON43646
NL-OMON43646已完成不适用

Characterizing the bone marrow environment in advanced-stage myelofibrosis. A PET/MRI study. - BEAMY

Vrije Universiteit Medisch Centrum0 个研究点目标入组 6 人开始时间: 待定最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
6

研究概览

简要总结

暂无简介。

研究设计

研究类型
Observational

入排标准

年龄范围
18 至 99(—)

入选标准

  • A diagnosis of primary-, post-polycythemia vera- or post-essential thrombocythemia MF (according to the 2008 WHO criteria)
  • A high- or intermediate-1 or -2 risk level (according to the IWG-MRT DIPSS criteria)
  • Fibrosis (grade 2-4) on bone marrow biopsy
  • A scheduled treatment with (and thus an indication and eligibility for) ruxolitinib

排除标准

  • Current or previous treatment with a JAK2 inhibitor
  • History of allogeneic stem cell transplantation
  • Contraindication for treatment with ruxolitinib (including a platelet count < 50,000/µL)
  • Contraindication for used imaging modalities
  • Inability to sign informed consent

研究者

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