Effect of Dexmedetomidine Versus Propofol on the Onset and Recovery of Sedation in Stereotactic Brain Biopsy A Comparative Study
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 入组人数
- 60
- 主要终点
- the sedation characteristics
研究概览
简要总结
Pre-operative anxiety leads to higher sympathetic stimulation. Propofol in the main drug used during interventional or imaging techniques that need sedation. Also, dexmedetomidine causes sedation, analgesia, sympatholytic properties, without respiratory depression.In stereotactic brain biopsy; patient discomfort due to drilling a hole through the skull and the advancement of the biopsy needle make the patient in need for good sedation and analgesia.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double (Participant, Investigator)
入排标准
- 年龄范围
- 20 Years 至 60 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- 未提供
排除标准
- 未提供
研究组 & 干预措施
Hemodynamic parameters
干预措施: dexmedetomidine/ propofol (Drug)
Ramsay sedation score
干预措施: dexmedetomidine/ propofol (Drug)
Intraoperative side effects
干预措施: dexmedetomidine/ propofol (Drug)
recovery of sedation
干预措施: dexmedetomidine/ propofol (Drug)
结局指标
主要结局
the sedation characteristics
时间窗: 4 hours
Ramsay sedation score
次要结局
未报告次要终点
研究者
Ghada M.Samir
assistant professor of anaesthesia and intensive care
Ain Shams University