跳至主要内容
临床试验/NCT02879292
NCT02879292Unknown不适用

Post-operative Outcomes in the Pyloromyotomy Procedure Under Spinal Anesthesia: A Retrospective Study in 100 Cases

Bnai Zion Medical Center0 个研究点目标入组 92 人开始时间: 2016年12月最近更新:
适应症

试验速览

阶段
不适用
入组人数
92
主要终点
Postoperative pain measure in numerical scale

研究概览

简要总结

Infantile hypertrophic pyloric stenosis (HPS) is one of the most common gastrointestinal medical emergencies.This retrospective study will review the files of all infants with HPS, who were treated by open pyloromyotomy under spinal anesthesia in the Bnai Zion Medical Center between the years 2006 to 2015.

详细描述

Infantile hypertrophic pyloric stenosis (HPS) is one of the most common gastrointestinal medical emergencies that occur during the first 2 months of life.

Anesthetic induction and airway management of infants with HPS can be challenging because of the accumulation of significant volumes of gastric content, predisposing these patients to pulmonary aspiration during the induction of general anesthesia Despite the correction of systemic metabolic alkalosis, cerebrospinal fluid can remain alkalotic, and in this context hyperventilation and opioids may increase the risks of post-operative central apnea. All of the above anesthetics risks urged some anesthetists to alternatively use spinal anesthesia (SA) in infants undergoing pyloromyotomy.

This anesthetic technique proved to be both safe and efficient in infants undergoing pyloromyotomy, in addition to decreasing the mentioned risks associated with the other techniques.

This retrospective study will review the files of all infants with HPS, who were treated by open pyloromyotomy under SA in the Bnai Zion Medical Center between the years 2006 to 2015. It is designed to evaluate the postoperative full enteral feeding time, pain management and the incidence of post-operative apnea, the incidence of substantial vomiting episodes and other spinal anesthesia complications as secondary outcomes in infants undergoing pyloromyotomy under spinal anesthesia.

研究设计

研究类型
Observational
观察模型
Case Only
时间视角
Retrospective

入排标准

年龄范围
4 Weeks 至 8 Weeks(Child)
性别
All
接受健康志愿者

入选标准

  • Infants with Hypertrophic Pylorostenosis, treated by open pyloromyotomy under Spinal Anesthesia

排除标准

  • Infants with Hypertrophic Pylorostenosis,treated by open pyloromyotomy under General Anesthesia

结局指标

主要结局

Postoperative pain measure in numerical scale

时间窗: till 24 hours after surgery

次要结局

  • Vomiting measure in numbers(till 24 hours after surgery)

研究者

申办方类型
Other Gov
责任方
Principal Investigator
主要研究者

LUIS.GAITINI

M.D.

Bnai Zion Medical Center

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