Characteristics of PUFAs Composition in Preterm Infants and Its Impact on Disease Prognosis

The First Hospital of Jilin University0 个研究点目标入组 600 人开始时间: 2023年9月21日最近更新: 2023年9月21日

适应症

试验速览

阶段: 不适用
状态: 尚未招募
发起方: The First Hospital of Jilin University
入组人数: 600
主要终点: Mortality and severe complications of premature infants

研究概览研究设计入排标准结局指标研究者记录与标识符相似试验

研究概览

简要总结

The research endeavors to examine the critical composition of Polyunsaturated Fatty Acids (PUFAs) in premature infants across different gestational stages and under varying disease conditions, and delineate the metabolic attributes of PUFAs in premature infants and their interplay with the onset of diseases. This study anticipates furnishing a theoretical foundation for the rationalization of PUFAs supplementation in premature infants and for informing strategies related to disease prevention and management.

研究设计

研究类型: Observational
观察模型: Cohort
时间视角: Prospective

入排标准

性别: All
接受健康志愿者: 否

入选标准

•Infants born between 24 and 36 weeks of gestational age who are admitted within 24 hours of birth, including both premature and full-term newborns.

排除标准

•Infants with severe congenital developmental abnormalities, those requiring external supplementation of PUFAs in addition to standard intravenous nutrition and breastfeeding, and those with a severe prognosis indicating non-survival during their hospitalization.

结局指标

主要结局

Mortality and severe complications of premature infants

时间窗: before discharge

incidence of death，NEC，PDA，BPD，IVH，PVL and sepsis

次要结局

Mortality(before discharge)
PVL(before discharge)
NEC(before discharge)
PDA(before discharge)
BPD(before discharge)
IVH(before discharge)
sepsis(before discharge)

研究者

发起方

The First Hospital of Jilin University

申办方类型

Other

责任方

Sponsor

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