ACTRN12623000279628招募中未知
Genetic and Biochemical Predictors of Pelvic Organ Prolapse
试验速览
- 阶段
- 未知
- 状态
- 招募中
- 入组人数
- 1,200
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18 Years 至 55 Years（—）
- 性别
- Female
入选标准
- •All participants (surgical and genome-only study):
- •1.Aged between 18 and 55
- •2. Women (including all people with female reproductive anatomy [but no history of male hormone therapy])
- •3.Able to give informed consent for participation
- •Prolapse group for both studies:
- •1. A previously or currently diagnosed POP-Q grade 3 or 4 pelvic organ prolapse
- •Surgical prolapse group:
- •1.Undergoing planned pelvic prolapse repair surgery
- •Surgical control group:
- •1. Undergoing a planned abdominal hysterectomy.
- •No further specific, inclusion criteria for the genome-only study
排除标准
- •All participants:
- •1. Diagnosed primary genetic disorder affecting connective tissue or a secondary disorder that affects connective tissue such as autoimmune diseases
- •Control group for both surgical and genome-only studies:
- •1. First degree relative with a previously or currently diagnosed (prior to age 55) POP-Q grade 3 or 4 pelvic organ prolapse
- •Surgical group (both prolapse and controls)
- •1.Taking anti-coagulant medications
- •2.Any medical condition that, in the assessment of the operating surgeon, contraindicates taking a tissue biopsy
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