NCT04019457已完成不适用
Cereals and Intestinal Function: Investigations in Healthy Participants
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 17
- 试验地点
- 1
- 主要终点
- Changes in parameters of intestinal barrier function
研究概览
简要总结
The aim of the present study is to determine the effect of dietary fiber on intestinal function in healthy subjects.
详细描述
In the intervention study normal weight participants will receive defined amounts of different cereal flakes for several days. Before and after intervention parameters of intestinal function will be assessed.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Basic Science
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 20 Years 至 60 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •BMI <25 kg/m2
- •daily alcohol consumption <20g (men) or <10g (women)
排除标准
- •food allergies or intolerances
- •instable body weight
- •BMI <18,5 kg/m2 or >25 kg/m2
- •bariatric surgery within the last 5 years
- •intake of antibiotics within the last month or during the study
- •daily alcohol consumption >20g (men) or >10g (women)
- •pregnancy and/or lactation period
- •viral or bacterial infection during the last three weeks
- •increased inflammatory markers of unknown reason
- •chronic or acute disease of gastrointestinal tract
结局指标
主要结局
Changes in parameters of intestinal barrier function
时间窗: 1 week
Changes in endotoxin plasma levels
次要结局
- Changes in blood lipid levels(1 week)
研究者
Prof. Dr. Ina Bergheim
Principal Investigator
University of Vienna
研究点 (1)
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