Collection of Cerebrospinal Fluid in Healthy Children
试验速览
- 阶段
- 不适用
- 状态
- 终止
- 入组人数
- 32
- 试验地点
- 1
- 主要终点
- Cerebrospinal fluid (CSF)
研究概览
简要总结
The purpose of this study is to obtain cerebrospinal fluid from healthy children already undergoing a lumbar puncture procedure at New York Presbyterian Hospital, to act as healthy controls when compared to children with late infantile neuronal ceroid lipofuscinosis (LINCL), a fatal neurodegenerative disease.
详细描述
obtain cerebrospinal fluid from healthy children already undergoing a lumbar puncture procedure at New York Presbyterian Hospital, to act as healthy controls when compared to children with late infantile neuronal ceroid lipofuscinosis (LINCL), a fatal neurodegenerative disease.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 2 Years 至 8 Years（Child）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Males and females, ages 2 yrs to 8 yrs
- •Children already undergoing a lumbar puncture procedure for clinical or diagnostic purposes
排除标准
- •Presence of any significant neurological diseases, as judged by the co-investigators
- •Presence of any significant medical conditions including cancer
结局指标
主要结局
Cerebrospinal fluid (CSF)
时间窗: 1 time point (once)
The primary study endpoint is the metabolic profiling of 32 samples of cerebrospinal fluid from healthy subjects, in comparison to 32 samples of CSF from children with LINCL, to determine whether there are biomarkers found in the cerebrospinal fluid that are associated with LINCL.
次要结局
未报告次要终点