Clinical Utility and Outcome Prediction of Cardiovascular Computed Tomography (PREDICT-CT)
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 4,200
- 试验地点
- 1
- 主要终点
- All-cause death.
研究概览
简要总结
In this study the investigators retrospectively and prospectively collect information from enrolled subjects undergoing CCTA and evaluate the association of cardiac and non-cardiac imaging with laboratory markers and clinical data including outcome.
详细描述
In this study the investigators retrospectively and prospectively collect information from enrolled subjects through a period of a total of 10 years to evaluate multidimensional associations between phenotypic manifestations of cardiovascular disease via CCTA and cardiac and non-cardiac imaging, serum biomarkers, demographic and clinical information, clinical presentation (cross-sectional), therapy changes (time-varying) and their ability to predict mortality and MACE (major adverse cardiac event ) (longitudinal) in patients clinically indicated for CCTA.
The aim is to establish a comprehensive cross-sectional, time-varying and longitudinal data collection for individuals undergoing clinically-indicated CCTA to date in order to apply novel multiparametric approaches to determine cardiovascular significance to clinically-important patient-centered events. For data collection this registry will follow a standard CRF (case report form) structure, so to enable the merging of this data-set with other international registries, which might contribute in overcoming some gaps of knowledge from previous CCTA studies.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Adult individual >18 years
- •Undergoing clinically indicated CCTA
- •Signed informed consent or waiver
排除标准
- 未提供
结局指标
主要结局
All-cause death.
时间窗: 10 years
The primary endpoint is the time to first occurrence of death from all-causes.
次要结局
- Other outcome(10 years)
- Major adverse cardiovascular events (MACE)(10 years)
