Effect of Tunneled Hemodialysis Catheter Antimicrobial Lock Solution in Prevention of Catheter Related Blood Stream Infection.
试验速览
- 阶段
- 2 期
- 状态
- 已完成
- 发起方
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- Comparison between both groups in terms of incidence of Catheter related blood stream infection
研究概览
简要总结
Tunneled hemodialysis catheters are susceptible to infection with high incidence of complication to the hemodialysis patients .The study aimed to prevent catheter infection through comparing use of antimicrobial solution (Taurolidine) when used as lock solution installed in the lumen of the catheter at the end of the hemodialysis session with the usually used lock solution heparin. The Study was performed on 100 hemodialysis patients over one year in Sohar hospital ,Oman .
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Crossover
- 主要目的
- Prevention
- 盲法
- None
入排标准
- 年龄范围
- 13 Years 至 —（Child, Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- 未提供
排除标准
- 未提供
研究组 & 干预措施
Group (B) patients used Taurolidine based lock solution as tunneled hemodialysis catheter lock
Measure incidence of catheter related blood stream infection while patients use Taurolidine based lock solution as catheter lock
干预措施: Taurolidine citrate 4% and heparin 500 (Drug)
结局指标
主要结局
Comparison between both groups in terms of incidence of Catheter related blood stream infection
时间窗: one year
The investigators have studied the incidence of catheter related bacterial infection in both groups to determine superior effectiveness of Taurolidine lock solution than Heparin lock only in terms of prevention of infection .
次要结局
- Comparison between both groups in terms of treatment cost(one year)
研究者
Ahmed Said Mohammed
Principal investigator
Oman Ministry of Health