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临床试验/NCT06900569
NCT06900569已完成不适用

Ashwagandha Supplementation for Recovery From Muscle-damaging Exercise and Sleep Quality

University of Saskatchewan1 个研究点 分布在 1 个国家目标入组 19 人开始时间: 2025年3月22日最近更新:
干预措施

试验速览

阶段
不适用
状态
已完成
入组人数
19
试验地点
1
主要终点
Change in isometric biceps strength measured with a dynamometer (Nm)

研究概览

简要总结

Ashwagandha is an herbal supplement that has a wide range of benefits related to exercise when supplemented for about 8-12 weeks. This study aims to investigate whether short-term Ashwagandha supplementation can enhance muscle recovery following exercise by measuring muscle strength recovery, swelling, and soreness in the biceps.

详细描述

The purpose of the study is to determine the effects of Ashwagandha supplementation on recovery from muscle-damaging exercise. Ten to twenty participants will be randomized to receive Ashwagandha supplementation (600 mg/d) or placebo for 10 days. On day 7, participants will perform a muscle damaging exercise session (six sets of concentric and emphasized eccentric repetitions with the biceps). Before and after exercise and at 24, 48, and 72 hours after exercise, isometric muscle strength, muscle swelling (ultrasound), and muscle soreness will be assessed. The investigators hypothesize the Ashwagandha will alleviate symptoms of muscle damage (swelling and soreness) and enhance strength recovery after a bout of muscle-damaging exercise.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Treatment
盲法
Triple (Participant, Investigator, Outcomes Assessor)

入排标准

年龄范围
18 Years 至 35 Years(Adult)
性别
All
接受健康志愿者

入选标准

  • male or female, aged 18-35y

排除标准

  • Conditions that may be affected by exercise (determined by "yes" answers to the "Get Active Questionnaire") Pregnant Breastfeeding
  • Allergies to:
  • Dicalcium Phosphate
  • Cellulose
  • Vegetable magnesium stearate

研究组 & 干预措施

Placebo

Placebo Comparator

600 mg/d placebo for 10 days

干预措施: Placebo (Dietary Supplement)

Ashwagandha

Experimental

600 mg/d Ashwagandha

干预措施: Ashwagandha (Dietary Supplement)

结局指标

主要结局

Change in isometric biceps strength measured with a dynamometer (Nm)

时间窗: 72 hours

次要结局

  • Change in muscle thickness measured with ultrasound (cm)(72 hours)
  • Change in muscle soreness measured with a visual analog scale with scores ranging from 0 (no soreness) to 10 (maximal soreness)(72 hours)
  • Change in sleep quality with the Pittsburgh Sleep Quality Index with scores ranging from 0 (no sleep problems) to 3 (lowest sleep quality)(10 days)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Phil Chilibeck

Professor

University of Saskatchewan

研究点 (1)

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