To assess the efficacy and evaluate the anti-inflammatory effects of Boswellia serrata extract in Osteoarthritis

Star Hi Herbs PvtLtd0 个研究点目标入组 100 人开始时间: 待定最近更新: 2024年5月27日

试验速览

暂无简介。

•1.Participants between 40 to 75 years
•2.Suffering from unilateral or bilateral OA of the knee within grade-2 according to the Kellgren-Lawrence Classification of Osteoarthritis
•3.Patients with a minimum pain visual analogue scale (VAS) score 3.5 to 7.4
•4.Lequesnes functional index between 5-7 points
•5.The Western Ontario McMaster Index (WOMAC) score should be less than or equal to 48
•6.Participants have to be able to walk and give both verbal and written information regarding the study
•7.Subjects willing to comply with the prescribed treatment regime for the duration of study participation.

•1.Expectations for surgery in the near future
•2.Patients who are on medication for OA.
•3.Known hypersensitivity to herbal extracts or dietary supplements
•4.Pregnant or lactating women and women of child bearing potential not following adequate contraceptive measure or women who were found positive for urine pregnancy test
•5.Non degenerative joint diseases or other joint degenerative diseases
•6.Incapacitated or bound to a wheelchair or bed and unable to carry out self ?care activities
•7.Current or recent (in the last 3 months) oral or intra ?articular corticosteroid therapy
•8.Pre-existing or recent onset of demyelinating disorders or type I diabetes
•9.Ongoing with anticoagulants, hydantoin, lithium, steroids, methotrexate, and colchicine
•10.Renal, hepatic, hematopoietic disease, hypertension, severe cardiac insufficiency, congestive heart failure and untreated hyperlipidemia (cardiovascular risk)
•11.Ayurvedic formulation or any form of complementary alternative medicine therapy in the preceding 2 months
•12.Receiving any investigational drug or participating in any other clinical trial that ended in preceding month or currently ongoing
•13.Patients who needed high dose of NSAIDs or analgesics; and
•14.Inability to comply with study procedures.

发起方

Star Hi Herbs PvtLtd