A double blind randomised placebo controlled clinical trial testing the effectiveness of a Chinese herbal medicine extract formulation for constipation-predominant Irritable Bowel Syndrome.

niversity of Western Sydney0 个研究点目标入组 160 人开始时间: 2009年7月8日最近更新: 2020年1月13日

适应症

试验速览

暂无简介。

•1. Have a normal colonic evaluation test within the previous 5 years (colonoscopy or barium enema, or other colonic imaging).
•2. Normal blood test results (full blood count, liver function test, urea & creatinine) performed within the last 3 months.
•3. Confirmed C-IBS diagnosis by a Gastroenterologist or General Practitioner (GP).

•1. Pregnancy or breast-feeding.
•2. Significant cardiovascular, renal, hepatic, pulmonary, endocrine, metabolic, or haematological disorders.
•3. Diabetes mellitus requiring insulin therapy.
•4. Epilepsy.
•5. Inflammatory bowel disease.
•6. Gastrointestinal tract neoplasm.
•7. Celiac disease (by Tissue Transglutaminase (TTG) performed in the previous five years).
•8. Current psychiatric illness or dementia (excluding clinically diagnosed depression or anxiety where the patient has been stable on medication for at least three months).
•9. Current alcoholism or drug abuse.
•10. Previous bowel surgery (excluding appendectomy, cholecystectomy, fundoplication).
•11. Any serious medical or psychological disorder likely to preclude completion of the trial.
•12. The use of Quinine, Digoxin, Thiazides, Potassium Sparing Diuretics, Ephedrine Hydrochloride, Iron-containing agents and Pancreatin drugs.
•13. Severe Idiopathic constipation.

发起方

niversity of Western Sydney