Sensory Processing in Subjects With Painful Bladder Syndrome
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 34
- 试验地点
- 1
- 主要终点
- This study proposes to examine the sensations that are produced by warming the skin, poking the skin, pressure on muscles and by applying a blood pressure cuff.
研究概览
简要总结
The purpose of this study is to determine if clinically relevant subsets exist in patients meeting the diagnosis of Painful Bladder Syndrome (PBS). Subsets suggest differential responses to treatments and if verified, this will be important for the stratification of patients in clinical studies related to PBS.
详细描述
Patients with the diagnosis of painful bladder syndrome (PBS) constitute two or more phenotypes that are distinguished by differential neurophysiological processing of sensory information. Further, these differing phenotypes can be predicted by the presence or absence of the co-morbidity fibromyalgia.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 年龄范围
- 19 Years 至 75 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •NIDDK criteria for Painful Bladder Syndrome
- •Age 19 years or older
- •Must be able to read and speak English since testing materials are validated in English
排除标准
- •PBS subjects must be independent of co-existing pain disorders or use of medications
- •Uncontrolled hypertension or significant cardiopulmonary disease
- •No chronic daily pain
- •Older than 75 years of age
结局指标
主要结局
This study proposes to examine the sensations that are produced by warming the skin, poking the skin, pressure on muscles and by applying a blood pressure cuff.
时间窗: One and half to two hours.
次要结局
未报告次要终点