Magnetic resonance enterography as a predictor of disabling disease in newly diagnosed Crohn's Disease

niversity College London0 个研究点目标入组 198 人开始时间: 2019年3月12日最近更新: 2023年2月13日

适应症

试验速览

2022 Protocol article in https://pubmed.ncbi.nlm.nih.gov/36192092/ (added 04/10/2022)

•METRIC cohort:
•1. Enrolled in the METRIC study, new diagnosis cohort AND
•2. Formed part of the final new diagnosis cohort (i.e. with a confirmed diagnosis of Crohn's disease and underwent relevant study interventions and follow-up). METRIC new diagnosis cohort inclusion criteria were:
•2.1. Aged 16 years or more
•2.2. Newly diagnosed with Crohn's disease based on endoscopic, histological, clinical and radiological findings, OR
•2.3. Highly suspected of Crohn's disease based on characteristic endoscopic, imaging and/or histological features but pending final diagnosis (only participants who ultimately were confirmed to have Crohn's disease will continue in this extension study) AND
•3. Have given signed consent to be part of METRIC-EF
•Retrospective cohort:
•1. Aged 16 years or more and received a new diagnosis of Crohn's disease based on endoscopic, histological, clinical and radiological findings
•2. Dedicated enteric imaging (either MRE or SBUS) acquired according to the standards of the METRIC study and performed either < 3 months after, or < 3 months prior to the new diagnosis of Crohn's disease
•3. Institutional practice is to perform MRE or SBUS in all patients with newly diagnosed Crohn's disease
•4. Has > 4 years clinical follow-up data, or anticipated to have such follow-up data by the time of consensus endpoint meetings (mid 2020)
•5. Have given signed consent to be part of METRIC-EF

发起方

niversity College London