Effects of Bacterial Vaginosis Treatment on the Vaginal Microbiota and Correlates of Treatment Failure (BV Study)

Bill and Melinda Gates Foundation0 个研究点目标入组 150 人开始时间: 2024年9月25日最近更新: 2026年8月3日

适应症

试验速览

暂无简介。

•Premenopausal women, 18 – 45 years old
•BV by Amsel criteria (at least 3 of 4 criteria must be present) and/or Nugent score (if symptomatic, score = 4, if asymptomatic = 7).
•HIV negative or positive (up to 20 people living with HIV will be included) based on antibody test at screening. • Not pregnant at screening/enrolment visit, and unlikely to have an early pregnancy per clinician’s assessment of last menstrual period and recent sexual activity.
•Literate, willing and able to provide written informed consent
•Willing and able to attend study visits and comply with study procedures, including self-sampling and completion of the daily diary

•STI positive for Chlamydia, gonorrhoea, symptomatic candidiasis or trichomoniasis positive at screening
•Pregnant women
•Illiterate women
•Women who have had antibiotic treatment within the last 7 days
•Clinically significant acute or chronic medical condition or other circumstance that in the opinion of the
•PI/designee makes the participant unsuitable for participation in the study or jeopardizes the safety or rights of the participant.

发起方

Bill and Melinda Gates Foundation