Ramadan and Energy (RAMEE) Study
试验速览
- 阶段
- 不适用
- 入组人数
- 200
- 试验地点
- 1
- 主要终点
- Resting metabolic rate
研究概览
简要总结
Ramadan fasting entails abstinence from eating and drinking between dawn and sunset. During this month major changes in meal times and patterns, sleeping times and activity occur. Starvation is known to lead to a compensatory reduction in energy expenditure. However, the Ramadan fast is not synonymous with starvation as it involves intermittent periods of fasting followed by gorging. People who fast during Ramadan feel less energetic. However, little is known about the effects of this religious practice on energy metabolism. .
The aim of this study is to assess energy dynamics before and/or after and during Ramadan fasting in non-obese participants. Resting metabolic rate (RMR), thermic effect of food (TEF), active energy expenditure (AEE) and total energy expenditure (TEE) in free-living conditions will be measured . Indirect calorimetry will be used to assess RMR and TEF, doubly labeled water will be used to measure TEE and activity monitors will measure physical activity. In addition, body composition analysis will be performed by bio-electrical impedance. Blood sample will be taken to exclude medical factors affecting energy metabolism.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 70 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Willing to participate.
- •Age (18-70) years.
- •BMI (20-30 kg/m2).
- •Physically and mentally healthy.
- •Consent form signed.
排除标准
- •Any patients with significant health problem.
- •Pregnant and lactating females.
- •Consumption of caffeine before tests.
- •Patients who have had vigorous exercise for the last 12 hours before visit.
- •Patients with diabetes treated with drugs known to alter the metabolic rate.
- •Patients who had bariatric surgery.
- •Patients with eating disorders.
- •Patients with conditions known to affect energy expenditure
- •Patients on medication know to alter EE (Thyroxine, anti-thyroid drugs, certain cold remedies)
结局指标
主要结局
Resting metabolic rate
时间窗: 3 months
24 hour energy expenditure
时间窗: 3 months
次要结局
未报告次要终点