Predictive Factors for Initial MMSE Score and Rapid Decline in Alzheimer's Disease Patients
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- Change in MMSE Score Over 12 Months - measured as either a decrease of ≥3 points on the Mini-Mental State Examination [MeSH] or patient institutionalization within 12 months.
研究概览
简要总结
This study looks at people with Alzheimer's disease to find out which factors are linked to their initial score on the Mini-Mental State Examination (MMSE) and which factors may predict a fast decline in their score over 12 months. Researchers will review medical records from patients seen at the Memory Clinic of Gonesse Hospital and analyze information such as age, education, medical history, nutrition, mood, and caregiver burden. The goal is to better understand what influences early cognitive performance and how quickly it changes, to help improve patient care and planning.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Confirmed diagnosis of Alzheimer's disease according to NIAA 2018 or IWG 2021 criteria
- •At least two MMSE evaluations spaced 12 months apart
- •Follow-up at the Memory Clinic of CH Gonesse
排除标准
- •Presence of other neurodegenerative diseases (e.g., Frontotemporal Dementia, Multiple System Atrophy, Vascular Dementia, LATE)
- •Patient has moved out of the study area (outside the CH Gonesse territory)
结局指标
主要结局
Change in MMSE Score Over 12 Months - measured as either a decrease of ≥3 points on the Mini-Mental State Examination [MeSH] or patient institutionalization within 12 months.
时间窗: 12 months
次要结局
未报告次要终点