Correlation Between COVID-19 and Radiation Pneumonitis in Breast Cancer: A Historical Cohort Study
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 200
- 试验地点
- 1
- 主要终点
- Radiation Pneumonitis Situation
研究概览
简要总结
This study was designed as a single-center retrospective analysis aimed at investigating whether COVID-19 infection increases the risk or burden of radiation-induced pneumonitis in breast cancer patients.
详细描述
This study was designed as a single-center retrospective analysis aimed at investigating whether COVID-19 infection increases the risk or burden of radiation-induced pneumonitis in breast cancer patients. Breast cancer patients who underwent radiotherapy at the Cancer Center of Zhejiang Hospital between January 1, 2021, and June 30, 2024, were screened for eligibility. Patients who met the inclusion criteria were identified through the hospital information system, and their clinical records were reviewed. Follow-up was conducted via telephone interviews.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 80 Years（Adult, Older Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •patients with pathologically or cytologically confirmed primary breast cancer,
- •aged 18 years or older but younger than 80 years,
- •with complete and reliable medical records,
- •for those with COVID-19 infection, documented evidence of a positive test result.
排除标准
- •concomitant pulmonary malignancies,
- •a history of prior thoracic radiotherapy,
- •concurrent pulmonary infections other than COVID-19 during radiotherapy,
- •missing key data with loss to follow-up,
- •or any other condition considered unsuitable for enrollment by the investigators.
结局指标
主要结局
Radiation Pneumonitis Situation
时间窗: From January 2021 to June 2024
The incidence rate, severity and onset time of radiation pneumonitis
次要结局
未报告次要终点