NCT07638878进行中（未招募）不适用
Exploring the Efficacy of Tislelizumab Combined With Albumin-bound Paclitaxel and Platinum-based Chemotherapy in Patients With KRAS-mutated Lung Cancer Who Are Ineligible for Curative Surgery
Guangzhou Medical University1 个研究点 分布在 1 个国家目标入组 30 人开始时间: 2020年11月6日最近更新:
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
- 发起方
- 入组人数
- 30
- 试验地点
- 1
研究概览
简要总结
To determine the optimal objective response rate (ORR) of tislelizumab combined with albumin-bound paclitaxel and platinum agents in patients with KRAS-mutant lung cancer who are ineligible for curative surgery
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Other
入排标准
- 年龄范围
- 18 Years 至 75 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Ages 18-75 years (inclusive), regardless of gender;
- •Locally advanced (Stage IIIB, IIIC) or metastatic (Stage IV) non-small cell lung cancer (NSCLC) confirmed by histology as inoperable for curative intent (according to the 8th edition of the IASLC TNM staging system);
- •Or histologically confirmed inoperable mixed small cell lung cancer containing non-small cell lung cancer components;
- •KRAS gene mutation-positive;
- •KRAS mutation-positive lung cancer not amenable to radical surgery, treated with tislelizumab in combination with nab-paclitaxel and platinum chemotherapy.
排除标准
- •Patients with incomplete key baseline information and treatment data.
- •Patients who refuse to provide written informed consent (ICF).
研究者
Haihong Yang, MD, Pricipal investigator
Chief Physician
Guangzhou Medical University
研究点 (1)
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