Dexamethasone Therapy for Low Back Pain
试验速览
- 阶段
- 不适用
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- Pain Reduction
研究概览
简要总结
The study will evaluate the efficacy of IV Dexamethasone in treatment low back pain as an adjunct to analgesics.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •No "red flags" of serious spinal pathology
- •Normal neurological examination
- •Indication for opioid analgesia based on our pain management protocol
- •No known hypersensitivity to the medication
- •Ability to provide informed consent
排除标准
- •Pregnancy
- •All others who do not meet inclusion criteria
研究组 & 干预措施
Dexamethasone Therapy
Three consecutive doses of IV Dexamethasone with be administered over three days. The doses will be tapered according to the following: 1st dose, 26mg., 2nd dose, 20mg., and the third dose will be 10 mg. Each dose will be administered over 24 hours in a slow drip, in a 100cc. normal saline bag (0.9%).
干预措施: IV Dexamethasone Therapy (Drug)
Placebo Therapy
Three consecutive doses of 100cc IV normal saline (0.9%), will be administered over three days. Each dose will be administered over 24 hours in a slow drip.
干预措施: IV Normal Saline (NaCl 0.9%) (Other)
结局指标
主要结局
Pain Reduction
时间窗: Four days
Pain will be measured according to the Visual Analog Scale throughout the treatment.
次要结局
未报告次要终点