Attenuation of Haemodynamic Responses to Laryngoscopy and Endotracheal Intubation (Before and Elective Surgery): A Comparative Study Between Intravenous Esmolol and 4% Lignocaine Nebulisation - NI

Datta Meghe Institute of Higher Education and Research0 个研究点目标入组 0 人开始时间: 待定最近更新: 2024年7月22日

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•Participants meeting specific criteria were included in the study. These criteria encompassed individuals aged between 15 to 60 years, falling within American Society of Anesthesiologists (ASA) physical status classification I and II, scheduled for elective Ear, Nose, and Throat (ENT) surgical procedures. Additionally, inclusion required participants to have provided valid informed consent, ensuring their understanding and willingness to participate in the study. These criteria aimed to establish a homogeneous participant group suitable for the investigation into the comparative efficacy of intravenous Esmolol and 4% Lignocaine nebulization in attenuating haemodynamic responses during laryngoscopy and endotracheal intubation.

•Participants were excluded from the study if they did not meet the predefined inclusion criteria, including age, ASA status, and surgical type. Additionally, individuals with anticipated difficult intubation, uncontrolled hypertension or diabetes, a history of cardiac illness, neuromuscular disorders, hepatic disease, renal disease, known sensitivity to the drugs under investigation, cerebrovascular disease, or undergoing emergency surgery were excluded. Furthermore, patients with bronchial asthma or those currently receiving alpha and beta blockers were also excluded from participation. These exclusion criteria were established to mitigate confounding factors and ensure the safety and integrity of the study outcomes.

发起方

Datta Meghe Institute of Higher Education and Research