Perfusion and Functional Results After Pulmonary Artery Reconstruction During Oncologic Lung Resection
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 81
- 试验地点
- 1
- 主要终点
- Impact of pulmonary artery reconstruction on perfusion on the remaining lung lobe (ventilation/perfusion scan)
研究概览
简要总结
Lung cancer is the leading cause of cancer death worldwide. Despite the evolution of medical and multimodal treatments, surgical treatment remains the curative management in the localized cancer.
Historically, in central lung tumors, pneumonectomy was the gold standard. Currently, bronchial sleeve lobectomy is recommended as first-line treatment over pneumonectomy when complete resection is possible (Grade 2C).
In the case of pulmonary artery invasion, lobectomy with arterial resection and reconstruction is now an accepted option for central localized cancer.
Despite surgical challenge, arterial sleeve lobectomy is oncologically comparable with pneumonectomy while avoiding the high morbi-mortality.
Indeed, this surgery has shown better results than pneumonectomy in terms of overall survival, post-operative mortality, and quality of life.
Initially performed in patients with impaired cardio-pulmonary reserves, this parenchymal sparing procedure can be realised in all patients, when anatomical conditions allow a complete resection.
In the literature, no study has yet specifically investigated postoperative respiratory function after arterial sleeve lobectomy.
The investigators designed a retrospective monocentric study at the University Hospital of Montpellier on 81 lobectomies with pulmonary artery sleeve resection for lung cancer, from January 2001 to December 2020.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 —(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •all major lung resection with pulmonary artery reconstruction for lung cancer
- •from January 2001 to December 2020 at University Hospital of Montpellier
- •patient > 18 years
排除标准
- 未提供
结局指标
主要结局
Impact of pulmonary artery reconstruction on perfusion on the remaining lung lobe (ventilation/perfusion scan)
时间窗: 2001-2020
Comparison of perfusion data on pre and post operative ventilation/perfusion scan
次要结局
- pulmonary artery reconstruction patency(2001-2020)
- Impact of pulmonary artery reconstruction on pulmonary function(2001-2020)
- Pulmonary function according to the type of reconstruction(2001-2020)
研究者
Aude NGUYEN
Thoracic surgery resident
Centre Hospitalier Régional Universitaire Montpellier
