Clinical efficacy of epinastine hydrochloride ophthalmic solution for allergic conjunctivitis - Clinical efficacy of epinastine hydrochloride ophthalmic solution for allergic conjunctivitis

50 patients with allergic conjunctivitis wearing CL were instilled for 8 weeks with BAK-free epinastine hydrochloride ophthalmic solution, and clinical efficacy and safety were examined. Itchy eye, conjunctival hyperemia and staining score of kerato and conjunctival membrane were significantly improved by ocular instillation on CL wearing, which results were similar to the previous reports. Ocular instillation on CL wearing highly satisfied the patients with allergic conjunctivitis, which resulted in the CL wearing time extended to the same level as before the morbidity.Furthermore, eye drop instillation on CL wearing didn't have harmful effects on CL fitting, there were no adverse events such as corneal and conjunctival epithelial disorder, which suggested no concern in safety. From the above results, it can be expected that ocular instillation on CL wearing with epinastine hydrochloride ophthalmic solution can be a treatment for improving the symptoms and clinical findings of allergic conjunctivitis without impairing safety and increasing patient satisfaction.