NCT07146282尚未招募不适用
Vitamin K Antagonist in Rheumatic Heart Disease Patients With Mechanical Heart Valves: Our Current Status
Ahmed Hassan Rostom Ibrahim0 个研究点目标入组 165 人开始时间: 2025年9月1日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 165
- 主要终点
- Time in therapeutic range (TTR) for warfarin.
研究概览
简要总结
VKA in RHD patients with MHV: our current status
详细描述
Vitamin K Antagonist in Rheumatic heart disease patients with mechanical heart valves: Our Current Status
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Confirmed presence of a mechanical heart valve.
- •Aged ≥18 years
排除标准
- •Pregnancy.
- •Active bleeding disorders.
- •Severe liver/kidney disease (if affecting anticoagulation).
结局指标
主要结局
Time in therapeutic range (TTR) for warfarin.
时间窗: Baseline
TTR status will be calculated using the most recent INR value and patient records to determine whether INR is within the target therapeutic range (2.0-3.5) at the time of data collection.
2. Correlation Between TTR and Patient-Specific Factors
时间窗: Baseline
Assesses the relationship between INR control and factors such as age, comorbidities, adherence, vitamin K intake, and medication use based on data collected at the single study visit.
次要结局
- 1. Number of Participants With Reported Bleeding Events (Major or Minor)(Baseline)
- Number of Participants With Thromboembolic Events(Baseline)
- Rate of Patient Adherence to Warfarin Therapy(Baseline)
研究者
Ahmed Hassan Rostom Ibrahim
principal investigator
Assiut University
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