NCT03955913已完成不适用
Biomarker Study to Identify Subjects With Urothelial Cancer and Fibroblast Growth Factor Receptor Gene Aberrations
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 3,679
- 试验地点
- 199
- 主要终点
- Percentage of Participants with Selected Fibroblast Growth Factor Receptor (FGFR) Gene Aberrations
研究概览
简要总结
The purpose of this non-interventional study is to identify participants with urothelial cancer (UC) and selected fibroblast growth factor receptor (FGFR) aberrations through molecular testing of their archival tumor tissue.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Transitional cell carcinoma of the urothelium. Urothelial cell carcinoma (UCC) variants are allowed, that is, UCC with squamous and/or glandular differentiation, micropapillary, nested, plasmacytoid, neuroendocrine, and sarcomatoid
- •Diagnosis of one of the following: a) Metastatic or surgically unresectable urothelial cancer (UC) (Stage IV) or, b) localized surgically-resectable or resected UC with a T classification of T2 or above or non-muscle-invasive urothelial carcinoma of the bladder (Ta, T1 and carcinoma in situ [CIS])
- •Available archival tissue sample for fibroblast growth factor receptor (FGFR) aberration analysis
排除标准
- 未提供
结局指标
主要结局
Percentage of Participants with Selected Fibroblast Growth Factor Receptor (FGFR) Gene Aberrations
时间窗: Up to 3.9 years
Percentage of participants with selected FGFR gene aberrations will be assessed through molecular testing of their archival tumor tissue.
次要结局
未报告次要终点
研究者
研究点 (199)
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