Advancing Dupuytren's Contracture Treatment: a Clinical Prospective Study on Ultrasound-Guided Needle Knife Dissection
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 30
- 试验地点
- 2
- 主要终点
- Improvement in hand Function
研究概览
简要总结
This study aims to evaluate the efficacy and safety of ultrasound-guided needle knife dissection in treating Dupuytren's contracture. The procedure is designed to improve hund function and minimize complications associated with the conventional surgical methods.
详细描述
Dupuytren's contracture is a disease mainly characterized by the progressive fibrosis of the palmar fascia with subsequent hand deformity and dysfunction. The current study seeks to explore, through this minimally invasive technique, ultrasound-guided needle knife dissection regarding ROM and patient satisfaction. The procedure will be carried out under ultrasound guidance to ensure safety and completeness with the accuracy of precise dissection. Primary outcome measures will concern hand mobility, and secondary measures will evaluate patient self-reported satisfaction and any complications for the 6-month follow-up period.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Participants diagnosed with Dupuytren's Contracture.
- •Willing to undergo ultrasound-guided needle knife dissection
排除标准
- •Patients who have undergone previous surgery or needle apponeurotomy for Dupuytren's Contracture on the same hand.
- •Active hand infections, open wounds, or dermatological conditions in the treatment area.
- •Coagulopathy or use of anticoagulant that cannot be safely paused
- •Neuromuscular disorders affecting hand function
- •Pregnancy or breastfeeding
- •Uncontrolled systemic illnesses, such as poorly managed diabetes or cardiovascular disease.
- •Known hypersensitivity to local anesthetics.
结局指标
主要结局
Improvement in hand Function
时间窗: 6 months
Functional Improvement: - Evaluated using the QuickDASH score (0-100 scale).
Improvement in hand mobility
时间窗: 6 months
Range of Motion (ROM): - Measurment of joint mobility in degrees at MCP and PIP joints by goniometer.
次要结局
- Patient Satisfaction(6 months)
- Rate of procedure-related complications(6 months)
研究者
Mohamed Maher Ismail Ahmed Elashmawy
Lecturer of Rheumatology, Physical Medicine and Rehabilitation
Mansoura University Hospital