Biological Sample Collection for Research and Biobanking
试验速览
- 阶段
- 不适用
- 状态
- 终止
- 发起方
- 入组人数
- 1,279
- 试验地点
- 1
- 主要终点
- Establishment of a diverse bank of biological samples, stem cell lines, derivatives, and associated information.
研究概览
简要总结
The New York Stem Cell Foundation (NYSCF) Research Institute is performing this research to study different conditions and diseases by using cells from the body (such as skin or blood cells). NYSCF uses these samples to make stem cells and other types of cells, conduct research on the samples, perform genetic testing, and/or store these samples for future use.
Through this research, scientists hope to identify future treatments or even cures.
详细描述
Researchers at NYSCF study diverse diseases, conditions, and traits by creating "pluripotent" stem cells. These stem cells can become any cell in the human body, including cells that may be difficult, invasive, or even impossible to obtain directly. For example, researchers may create pancreatic insulin-producing cells to learn more about type 1 diabetes, or brain cells to learn more about Parkinson's disease.
Additionally, researchers perform genetic testing to learn more about DNA, a material in most cells that contains instructions for the body's development and functions (such as traits like eye color and risk of certain diseases). A piece of DNA that determines the specific role of a cell is called a "gene." If the instructions in a gene are abnormal, this can lead to disease.
Participation in the study involves: (1) completion of a health questionnaire, (2) providing a skin and/or blood sample from which stem cells may be created, (3) possible collection of a saliva sample for genetic analysis, and (4) possible future follow-up to provide additional information or learn about other research studies.
This study is not a clinical trial.
研究设计
- 研究类型
- Observational
- 观察模型
- Other
- 时间视角
- Prospective
入排标准
- 年龄范围
- 1 Month 至 100 Years（Child, Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •18 years or older or
- •Minor with parent/guardian consent
- •Biological Sample Collection
- •Able and willing to provide:
- •new samples of blood, skin, and/or saliva specifically for use in this study and/or
- •excess/leftover samples, cell lines, and/or derivatives that were (or will be) collected for reasons other than this study
排除标准
- •Non-English speaking
- •Wards of the state
- •For skin samples collected specifically for this study: history of keloid formation, bleeding disorder, allergy to the anesthetic, or anticoagulation use that precludes sample collection.
- •For blood samples collected specifically for this study: bleeding disorder, or other medical condition, if the subject's condition increases the risks associated with blood collection.
- •For saliva samples: inability to produce sufficient saliva or has a condition that precludes sample collection (such as severe trismus).
- •For prospective samples: refuse to adhere to NYSCF's and/or collaborating site's COVID-19 safety protocols during the COVID-19 pandemic.
结局指标
主要结局
Establishment of a diverse bank of biological samples, stem cell lines, derivatives, and associated information.
时间窗: Baseline
There are no primary endpoints planned for this biobank; endpoints will be specific to research projects that utilize samples/data contained in the biobank. Projects may investigate the biology, etiology, manifestations, progression, risk factors, genetic underpinnings, and treatment of diseases, conditions, and traits.
次要结局
未报告次要终点
研究者
Laura Andres-Martin
Senior Research Investigator
New York Stem Cell Foundation Research Institute