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临床试验/NCT02550951
NCT02550951Unknown不适用

Utility of Magnetic Resonance Lymphangiography in Postoperative Follow-up of Lymphedema: Comparison With Lymphoscintigraphy

Seoul National University Hospital1 个研究点 分布在 1 个国家目标入组 7 人开始时间: 2014年10月1日最近更新:
适应症
干预措施

试验速览

阶段
不适用
入组人数
7
试验地点
1
主要终点
pattern of lymph drainage (Scale of 0 to 5)

研究概览

简要总结

Its usefulness in implementing magnetic resonance angiography for postoperative follow-up of lymph lymphedema should try to evaluate and compare lymphoscintigraphy.

详细描述

Surgical methods include " surgical procedure to make a good lymphatic drain 'and' surgical resection with lymph tissue swelling , significant that two of lymphedema .In recent years, began receiving the spotlight this former method using micro-surgery , inde essential that in order to increase the success rate of these micro-surgery accurately assess the structural abnormalities of preoperative lymphatic and establishing the surgical plan , the primary diagnostic imaging examination of existing lymphedema Since the nuclear medicine examination as to obtain an accurate anatomical information it is also ideal for imaging in the preoperative assessment of lymphedema is precisely that you can not .

In contrast magnetic resonance lymphangiography recently developed a new magnetic resonance imaging techniques that many advantages in precision assessment of lymphedema patients.

First, there are high spatial resolution magnetic resonance lymphangiography through the lymphatic vessels to obtain the correct anatomical information .

Second, magnetic resonance lymphangiography is provide not only information about the functional status of the lymphatic anatomical information .

Third, the magnetic resonance lymphangiography minimally invasive techniques , without exposure to radiation , is relatively easy and safe , that there is a great advantage of being able to diagnose the structural and functional at the same time or later in lymphatic vessels.

研究设计

研究类型
Interventional
分配方式
Non Randomized
干预模型
Single Group
主要目的
Diagnostic
盲法
None

入排标准

年龄范围
20 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者
是

入选标准

  • •At least 20 years of age
  • •Patients underwent preoperative and receive magnetic resonance lymphangiography and Lymphoscintigraphy At the postoperative 3 months

排除标准

  • •Patients with a history of adverse effects on magnetic resonance contrast agents
  • •Patients with a Decreased renal function(Glomerular filtration rate <30 mL / min)
  • •Other, maternity, patients with a pacemaker or a cochlear

研究组 & 干预措施

pre-operation Lymphedema

Experimental

before magnetic resonance imaging(MRI), GADOVIST PFS [Bayer Korea] 7.5mL and local anesthetics 0.5m L mixed. and then 24 gauge needle using about 1 mL by the first , and second , the third the space between the toes intradermal injection , and then about 1-2 minutes , and massage the injection site, and Acquiring an image(coronal T1-weighted three-dimensional gradient-echo sequence) of the foot from a range including up to the pelvis from the comparison with lymphoscintigraphy

干预措施: lymphangiography (Procedure)

post-operation Lymphedema

Experimental

before magnetic resonance imaging(MRI), GADOVIST PFS [Bayer Korea] 7.5mL and local anesthetics 0.5m L mixed. and then 24 gauge needle using about 1 mL by the first , and second , the third the space between the toes intradermal injection , and then about 1-2 minutes , and massage the injection site, and Acquiring an image(coronal T1-weighted three-dimensional gradient-echo sequence) of the foot from a range including up to the pelvis from the comparison with lymphoscintigraphy

干预措施: lymphangiography (Procedure)

结局指标

主要结局

pattern of lymph drainage (Scale of 0 to 5)

时间窗: After magnetic resonance lymphangiography scans in up to 2years

0(abnormal)-10(normal)

delay of lymph drainage (Scale of 0 to 10)

时间窗: After magnetic resonance lymphangiography scans in up to 2years

0(delay)-10(normal)

depiction of lymph vessels (Scale of 0 to 10)

时间窗: After magnetic resonance lymphangiography scans in up to 2years

0(Not clarity)-10(Clarity)

enhancement of inguinal lymph nodes (Scale of 0 to 10)

时间窗: After magnetic resonance lymphangiography scans in up to 2years

0(Not clarity)-10(Clarity)

Visibility of Lymphatic Duct (Scale of 0 to 10)

时间窗: After magnetic resonance lymphangiography scans in up to 2years

0(Invisible)-10(Clearly visible)

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Seung Hong Choi

SeoulNUH

Seoul National University Hospital

研究点 (1)

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