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临床试验/NCT06390891
NCT06390891已完成不适用

Importance of Patient Characteristics in Identifying and Selecting Patients Suitable for Pancreatic Resection

Medizinische Hochschule Brandenburg Theodor Fontane0 个研究点目标入组 86,073 人开始时间: 2010年1月1日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
86,073
主要终点
In-hospital mortality

研究概览

简要总结

Pancreatic surgery is complicated and risky, especially for pancreatic cancer. It's been noticed that having these surgeries done at specialized centers can lead to better outcomes and survival rates. However, factors like patient selection and hospital conditions also play an important role. Some studies show that more surgeries done at a hospital might not always mean better results, as the type of patients and procedures can vary. To understand this better, the present study compared outcomes and patient characteristics between high-volume pancreatic centers and others.

详细描述

The study utilized German nationwide administrative data (diagnosis-related group statistics) spanning from 2010 to 2018. Persons who underwent pancreatic resections during this period were included, with exclusions for certain criteria like underage and type of procedure. Various factors including patient demographics, diagnoses, procedures, and comorbidities were analyzed to assess in-hospital mortality rates. High-volume pancreatic centers (HVPCs) were identified as those performing at least 50 procedures annually. Statistical analyses included comparing crude and adjusted mortality rates and assessing patient characteristics between HVPCs and non-HVPCs. Models were adjusted for multiple variables, and methods like the Cochran-Armitage trend test and mixed models were employed. Additionally, the study investigated how differences in patient characteristics between HVPCs and non-HVPCs affected mortality rates.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Retrospective

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • partial or total pancreatic resections between 2010 and 2018

排除标准

  • childhood (<18 years)
  • subjects with a pancreatic transplantation procedure
  • missing information on age or gender

结局指标

主要结局

In-hospital mortality

时间窗: 30 days

Death

次要结局

未报告次要终点

研究者

发起方
Medizinische Hochschule Brandenburg Theodor Fontane
申办方类型
Other
责任方
Principal Investigator
主要研究者

Rene Mantke

Head of Surgery

Medizinische Hochschule Brandenburg Theodor Fontane

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