Microcirculation in Perforator Flaps. Enhancing Tissue Survival
试验速览
- 阶段
- 早期 1 期
- 发起方
- 入组人数
- 50
- 试验地点
- 2
- 主要终点
- Mean pixel intensity using dynamic laser-induced-fluorescence-videoangiography
研究概览
简要总结
The aim of the present study is to assess the microcirculatory changes in the distal part of the perforator flap using ICG fluorescence angiography.
详细描述
Perforator flaps are increasingly used in reconstructive surgery both as pedicled and free flaps, mostly because of reduced donor site morbidity and superior aesthetic result. However, the there is still much to learn about the hemodynamic changes within these flaps.The aim of the present study is to assess the microcirculatory changes in the distal part of the perforator flap using ICG fluorescence angiography.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Single Group
- 主要目的
- Basic Science
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •patients submitted to elective abdominoplasty
排除标准
- •body mass index < 30 kg/m2
- •morbidly obese
- •patients with comorbidity such as diabetes
- •vascular disease
- •patients < 18 years, and patients using anti-coagulant therapy
- •severe hepatic insufficiency were excluded and a history of allergic reactions to ICG and iodide.
结局指标
主要结局
Mean pixel intensity using dynamic laser-induced-fluorescence-videoangiography
时间窗: dec. 2008--des 2010
Perfusion measurements were conducted intraoperatively by assessing microcirculation using the technique of dynamic laser-induced-fluorescence-videoangiography (IC-VIEW, PULSION Medical Systems AG, Munich, Germany).
次要结局
未报告次要终点