Assessment of sub-endometrial blood flow parameters following dydrogesterone and micronized vaginal progesterone administration in women with idiopathic recurrent spontaneous miscarriage

A prospective clinical study is being conducted at Institute of Reproductive Medicine, Kolkata, India. The aim is to evaluate differences in utero-placental blood flow and pregnancy outcome in women with Recurrent Spontaneous Miscarriage following administration of two types of progestins viz. micronised vaginal progsterone and oral dydrogesterone. 101 women who have had three or more consecutive miscarriages within first trimester, followed by spontaneous conception, are participating in this study. Endometrial blood flow parameters by Doppler indices and ongoing pregnancy rates are being studied.