Outcome of Treatment With Botulinum toxinA in Patients With Temporomandibular Myofascial Pain
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 发起方
- 入组人数
- 118
- 试验地点
- 1
研究概览
简要总结
Purpose: The aim of this study is to investigate the effectiveness and patient reported outcomes (interincisal distance and temporomandibular myofascial pain) of treatment with intramuscularly administered BTX-A vs N/S in patients with temporomandibular myofascial pain. OBJECTIVES: To determine the outcome of treatment with botulinum toxin-A vs N/S in patients with temporomandibular myofascial pain.
详细描述
OPERATIONAL DEFINITIONS:
Temporomandibular myofascial pain: Presence of any one or more of the following plus positives:
Pain in the Jaw Muscles: Persistent or recurrent pain located in the muscles of mastication (muscles that move the jaw).
Tenderness on Palpation: The pain is associated with tenderness that is identified during palpation of the affected muscles, particularly in the masseter, temporalis.
Limited Range of Motion: Patients often exhibit a reduced range of motion in the jaw.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double (Participant, Care Provider)
入排标准
- 年龄范围
- 18 Years 至 70 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients presenting with temporomandibular myofascial pain (VAS ≥ 6) for more than one month will be included.
- •Both genders.
- •Age 18-70 years
排除标准
- •Patient with history of allergic reactions with botulinum toxin-A.
- •Medically compromised patients. Current pregnancy.
- •Use of medication by the patients that could interfere with the effect of botulinum toxin-A (gentamycin, baclofen, atropine, revastigmine, verapamil, succinylcholine)
- •Neuromuscular disorders.
研究者
Azhar Ahmed
Outcome of treatment with botulinum toxinA in patients with temporomandibular myofascial pain
PAEC General Hospital, Islamabad