NCT01943981Unknown不适用
Exercise Performance in Patients With Atrial Fibrillation: Usefulness of Cardiopulmonary Exercise Test
Incheon St.Mary's Hospital1 个研究点 分布在 1 个国家目标入组 50 人开始时间: 2013年9月最近更新:
适应症
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 50
- 试验地点
- 1
- 主要终点
- Exercise response patterns of heart rate and oxygen uptake
研究概览
简要总结
Heart failure and stroke are the two major complication of atrial fibrillation. Current treatment for atrial fibrillation is so focused to stroke prevention, but the risk assessment for heart failure is less highlighted. The most of patients with atrial fibrillation have cardiac functional limitation of variable degree. We hypothesize that the exercise test would reveal the subclinical cardiac dysfunction, and might be helpful to classify the patients with atrial fibrillation according to their exercise capacity real cardiac function.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Prospective
入排标准
- 年龄范围
- 30 Years 至 80 Years(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Nonvalvular chronic atrial fibrillation
- •Left ventricular ejection fraction >40%
排除标准
- •Acute decompensated heart failure within 30 days
- •unstable hemodynamic status
- •Significant coronary artery disease
- •Any condition interfering sufficient exercise
- •Valvular stenosis or regurgitation of moderate or severe degree
- •Obstructive or restrictive lung disease of moderate or severe degree
- •Active malignancy
结局指标
主要结局
Exercise response patterns of heart rate and oxygen uptake
时间窗: At baseline
次要结局
- Composite cardiovascular events (all death, admission of heart failure, stroke/thromboembolism)(Up to 2 years)
研究者
Mi-Jeong Kim
Assistant professor
Incheon St.Mary's Hospital
研究点 (1)
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