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临床试验/NCT05244356
NCT05244356已完成不适用

Effective Public Health Communication to Influence COVID-19 Vaccination Intent and Message Propagation: A Randomized Controlled Experiment

Clinical Research Centre, Malaysia1 个研究点 分布在 1 个国家目标入组 5,784 人开始时间: 2021年4月29日最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
5,784
试验地点
1
主要终点
Change in intent to recommend the COVID-19 vaccine to healthy adults.

研究概览

简要总结

This is a randomised controlled experiment in the form of a web based survey study which randomly exposes participants to different forms of public health messages, after which participants will be assessed on their intent to take up the COVID-19 vaccine, recommend the vaccine, and also willingness to propagate the exposed message.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Other
盲法
Single (Participant)

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者
是

入选标准

  • •Willing and able to give informed consent for participation in the trial
  • •Malaysian nationality.
  • •Can understand either the English or Malay language.
  • •Aged 18 years or above

排除标准

  • •Received at least one COVID-19 vaccination dose

研究组 & 干预措施

Descriptive Norm (70%)

Experimental

Intervention in the form of a message likened to a social media post. Composed of 3 parts:

  1. Opening tag line highlighting the main concern that Malaysians have about the COVID-19 vaccine (safety and side effects)
  2. Message content describing that about 70% of Malaysians have expressed acceptance for the COVID-19 vaccine.
  3. Rally slogan: "It's safe and effective!"

干预措施: Health message exposure (Behavioral)

Descriptive Norm

Experimental

Intervention in the form of a message likened to a social media post. Composed of 3 parts:

  1. Opening tag line highlighting the main concern that Malaysians have about the COVID-19 vaccine (safety and side effects)
  2. Message content describing that the COVID-19 vaccine has been widely tested including with the elderly and people with existing health conditions, while subsequently highlighting that the vaccine was already received by millions worldwide.
  3. Rally slogan: "It's safe and effective!"

干预措施: Health message exposure (Behavioral)

Healthcare worker (HCW) recommendation

Experimental

Intervention in the form of a message likened to a social media post. Composed of 3 parts:

  1. Opening tag line highlighting the main concern that Malaysians have about the COVID-19 vaccine (safety and side effects)
  2. Message content highlights recommendation from Malaysian healthcare workers to get the vaccine, since majority of them has already received it, including the Malaysian Health Director General
  3. Rally slogan: "It's safe and effective!"

干预措施: Health message exposure (Behavioral)

Negative attribute framing

Experimental

Intervention in the form of a message likened to a social media post. Composed of 3 parts:

  1. Opening tag line highlighting the main concern that Malaysians have about the COVID-19 vaccine (safety and side effects)
  2. Message content describing the rate of side effects occurring with COVID-19 vaccination in a negative frame.
  3. Rally slogan: "It's safe and effective!"

干预措施: Health message exposure (Behavioral)

Positive attribute framing

Experimental

Intervention in the form of a message likened to a social media post. Composed of 3 parts:

  1. Opening tag line highlighting the main concern that Malaysians have about the COVID-19 vaccine (safety and side effects)
  2. Message content describing the rate of side effects occurring with COVID-19 vaccination in a positive frame.
  3. Rally slogan: "It's safe and effective!"

干预措施: Health message exposure (Behavioral)

Risky choice framing (Safety)

Experimental

Intervention in the form of a message likened to a social media post. Composed of 3 parts:

  1. Opening tag line highlighting the main concern that Malaysians have about the COVID-19 vaccine (safety and side effects)
  2. Message content describing a risky choice frame which compares the death rates occurring with COVID-19 vaccination versus contracting the virus itself.
  3. Rally slogan: "It's safe and effective!"

干预措施: Health message exposure (Behavioral)

Risky choice framing (Side effects)

Experimental

Intervention in the form of a message likened to a social media post. Composed of 3 parts:

  1. Opening tag line highlighting the main concern that Malaysians have about the COVID-19 vaccine (safety and side effects)
  2. Message content describing a risky choice frame that compares the incidence rates of blood clots occurring with COVID-19 vaccination versus contracting COVID-19.
  3. Rally slogan: "It's safe and effective!"

干预措施: Health message exposure (Behavioral)

Control message

Experimental

Control message containing only rally slogan: "It's safe and effective!"

干预措施: Health message exposure (Behavioral)

Combination message: Descriptive Norm (70%) + Descriptive Norm

Experimental

Participants received 2 messages which were exposed one at a time. Sequence of message appearing randomly rotated.

干预措施: Health message exposure (Behavioral)

Combination message: Descriptive Norm (70%) + HCW recommendation

Experimental

Participants received 2 messages which were exposed one at a time. Sequence of message appearing randomly rotated.

干预措施: Health message exposure (Behavioral)

Combination message: Descriptive Norm (70%) + Negative attribute framing

Experimental

Participants received 2 messages which were exposed one at a time. Sequence of message appearing randomly rotated.

干预措施: Health message exposure (Behavioral)

Combination message: Descriptive Norm (70%) + Positive attribute framing

Experimental

Participants received 2 messages which were exposed one at a time. Sequence of message appearing randomly rotated.

干预措施: Health message exposure (Behavioral)

Combination message: Descriptive Norm (70%) + Risky choice framing (Safety)

Experimental

Participants received 2 messages which were exposed one at a time. Sequence of message appearing randomly rotated.

干预措施: Health message exposure (Behavioral)

Combination message: Descriptive Norm (70%) + Risky choice framing (Side effects)

Experimental

Participants received 2 messages which were exposed one at a time. Sequence of message appearing randomly rotated.

干预措施: Health message exposure (Behavioral)

结局指标

主要结局

Change in intent to recommend the COVID-19 vaccine to healthy adults.

时间窗: Immediately before and after message exposure during questionnaire administration.

Outcome measure was assessed using a questionnaire answered through a 5 point ordinal scale. Scale ranges from "Strongly disagree", "Disagree", "Not sure", "Agree", and "Strongly agree".

Intent to share message on social media platform.

时间窗: Immediately after message exposure during questionnaire administration.

Outcome measure was assessed using a questionnaire answered through a 5 point ordinal scale.Scale ranges from "Strongly disagree", "Disagree", "Not sure", "Agree", and "Strongly agree".

Change in intent to accept the COVID-19 vaccine amongst the Malaysian adult population.

时间窗: Immediately before and after message exposure during questionnaire administration.

Outcome measure was assessed using a questionnaire answered through a 4 point ordinal scale. Scale ranges from '"Definitely no", "Not sure, but probably no", "Not sure, but probably yes"to Definitely yes".

Change in intent to recommend the COVID-19 vaccine to elderly.

时间窗: Immediately before and after message exposure during questionnaire administration.

Outcome measure was assessed using a questionnaire answered through a 5 point ordinal scale. Scale ranges from "Strongly disagree", "Disagree", "Not sure", "Agree", and "Strongly agree".

Change in intent to recommend the COVID-19 vaccine to people with existing health conditions.

时间窗: Immediately before and after message exposure during questionnaire administration.

Outcome measure was assessed using a questionnaire answered through a 5 point ordinal scale. Scale ranges from "Strongly disagree", "Disagree", "Not sure", "Agree", and "Strongly agree".

次要结局

  • Reliability of various information sources about COVID-19.(Immediately after message exposure during questionnaire administration.)
  • Moderators of vaccination intent.(Immediately after message exposure during questionnaire administration.)

研究者

发起方
Clinical Research Centre, Malaysia
申办方类型
Other
责任方
Principal Investigator
主要研究者

Nicholas Hing Yee Liang

Researcher, Principle Investigator, Pharmacist

Clinical Research Centre, Malaysia

研究点 (1)

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