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临床试验/NCT04559997
NCT04559997已完成不适用

6-year Follow-up Study of the Effectiveness of Neurorehabilitation Treatment in a Patient With Parkinson's Disease

Somogy Megyei Kaposi Mór Teaching Hospital2 个研究点 分布在 1 个国家目标入组 3 人开始时间: 2014年9月1日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
3
试验地点
2
主要终点
Timed up and Go test

研究概览

简要总结

Individualization of exercise is recommended but rarely performed in patients with Parkinson's disease (PD). Unusually High Intensity and Individual Sensor Motor with Visuomotor Mobility Trainer The clinical symptoms, mobility and posture of PD patients. After 3 weeks of intensive treatment, treated patients and the control group were subjected to a two-year observation. Objectives: The effect of the unusually highly intense and strictly individualized sensomotor and visuomotor agility program was determined for the clinical symptoms, mobility and stability of non-demented PD patients with a two-year follow-up. Detection and comparison of results of patients undergoing biphasic maintenance with the results of intensively treated patients and the control group. Patients were recalled every 3 months after the first intensive examination and one year after a one-year control. The results of the active group were continuously compared with the results of the passive and control groups, thus determining the effectiveness of our treatment and the deterioration of the other groups in life-quality. The treated groups will be divided into two. One Parkinson's group takes part in a treadmill treatment that takes place 3 times a week for 6 years. The other group does not undergo a special series of exercises after 3 weeks of intensive therapy. Main outcome measures: Movement disorder Society Unified Parkinson Disease Rating Scale, Motor Experiences of Daily Living, a measure sensitive to changes in a broad spectrum of PD symptoms. In group time, repeated measurements of variance analysis were compared to MDS-UPDRS M-EDL, Beck Depression Score, PDQ-39, EQ5D VAS, Schwab & England Scale for Parkinson's Disease. The TUG test and 12 static posturographic measurements are compared and compared to the healthy group as a standard. An at-limit and individualized sensorimotor and visuomotor agility exercise program vs. standard care, will improve non-demeted, stage 2-3 PD patient's clinical symptoms, mobility, and postural stability by functionally meaningful margins. As a long-term solution, a follow-up treatment can slow down the progression of clinical symtoms.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Treatment
盲法
None

入排标准

年龄范围
55 Years 至 85 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Parkinson's disease
  • Hoenh Yahr scale of 2-3
  • Instability problem

排除标准

  • Severe heart problems
  • Severe demeanor
  • Alcoholism
  • Drug problems

结局指标

主要结局

Timed up and Go test

时间窗: 6 year-long

Measuring the speed of walking

EQ5D-5L

时间窗: 6 years long

Questionnaire

posturography

时间窗: 6 year-long

body sway, Objective measurement of holding instability

次要结局

未报告次要终点

研究者

发起方
Somogy Megyei Kaposi Mór Teaching Hospital
申办方类型
Other
责任方
Principal Investigator
主要研究者

Tollár József

Dr. József Tollár, 7400 Kaposvár, Tallián Gy. u 20-32

Somogy Megyei Kaposi Mór Teaching Hospital

研究点 (2)

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