Exploring The Impact Of Inspiratory Muscle Training on Expiratory Muscle Thickness During Intensive Care Patients
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 30
- 试验地点
- 1
- 主要终点
- Abdominal Muscle Thickness
研究概览
简要总结
the specific effect of IMT on expiratory muscle strength and abdominal wall thickness during weaning remains unclear. To address this significant research gap, the primary objective of our study was to evaluate the effect of IMT after extubation on expiratory muscle strength and abdominal muscle thickness in respiratory ICU patients. On the other hand the investigators established reference values for ultrasonographic measurements in healthy control subjects as a comparative arm. To the best of our knowledge, this is the first study to examine the ultrasonographic effects of IMT on the expiratory muscle thickness after extubation. The investigators believe that our study may contribute to related literature in this context and guide future research as a pioneer with its unique value.
详细描述
the specific effect of IMT on expiratory muscle strength and abdominal wall thickness during weaning remains unclear. To address this significant research gap, the primary objective of our study was to evaluate the effect of IMT after extubation on expiratory muscle strength and abdominal muscle thickness in respiratory ICU patients. On the other hand the investigators established reference values for ultrasonographic measurements in healthy control subjects as a comparative arm. To the best of our knowledge, this is the first study to examine the ultrasonographic effects of IMT on the expiratory muscle thickness after extubation. The investigators believe that our study may contribute to related literature in this context and guide future research as a pioneer with its unique value. In this single-blind randomized controlled study, 20 patients were divided into two groups: IMT and conventional physiotherapy(CP). In order to establish normative data for abdominal muscle thickness, ten healthy controls were included in the study. The CP group received CP and the IMT group received CP+IMT for five days following extubation. The thicknesses of the external oblique abdominal(EOA),internal oblique sbdominal(IOA), transversus abdominus (TRA) and rectus abdominis (RA) muscleswere evaluated The maximum inspiratory pressure (MIP) and maximum expiratory pressure (MEP) were recorded.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double (Participant, Investigator)
入排标准
- 年龄范围
- 18 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •For Patients Group Inclusion Criteria:
- •Needing mechanical ventilation support longer than 2 days,
- •Alert and Riker Sedation Agitation Score >4
- •Being hemodynamically stable (HR<140 beats/min, BP stable)
- •Dobutamine and minimal vasopressor use
- •Fever of 36.5-38.5
- •Body Mass Index <40 m2/cm,
- •FiO2 of 0.5 or less,
- •Absence of myocardial ischemia.
排除标准
- •For Patients Group Exclusion Criteria:
- •Noncooperation
- •Phrenic nerve damage
- •Chest wall trauma and/or deformity to prevent diaphragmatic movement
- •Progressive neuromuscular disease with respiratory involvement
- •There is enough secretion to require more than one aspiration every hour.
- •Patients using sedative drugs continuously
- •High-dose cortisol use
- •Using a home mechanical ventilator before mechanical ventilation in intensive care unit
- •For Healthy Group Inclusion Criteria:
- •With the control and intervention group, age, characteristics and characteristics,
- •Chronic system and no ongoing treatment,
- •Body mass index not 40 kg/m2,
- •18-80 years old
结局指标
主要结局
Abdominal Muscle Thickness
时间窗: Change from baseline Maximal inspiratory and expiratory pressure at 5th day]
Eksternal Oblique, Internal Oblique, Transverses Abdominus and rectus abdominus Ultrasonografic mesasurements
次要结局
- Maximal inspiratory and expiratory pressure(Change from baseline Maximal inspiratory and expiratory pressure at 5th day])
研究者
Reyhan Kaygusuz
Principal Investigator
Istanbul Demiroglu Bilim University