Randomized double blind control trial between intrathecal Buprenorphine and intrathecal Fentanyl as an adjuvant to Bupivacaine in spinal anaesthesia for lower segment caesarean section
试验速览
- 阶段
- 3 期
- 状态
- 招募中
- 发起方
- 入组人数
- 80
- 试验地点
- 1
- 主要终点
- •post Operative regain of sensory block and motor block
研究概览
简要总结
The study is randomized, double blind, trial Comparing the efficacy between intrathecalbuprenorphine and Fentanyl as an adjuvant to bupivacaine in spinal anaesthesia in LowerSegment Cesarean Section for duration of sensory and motor block for surgery and duration of 1st rescue analgesia in post operative period and number of analgesic requirements in 24 hours postoperatively.
研究设计
- 研究类型
- Interventional
- 分配方式
- Coin toss, Lottery, toss of dice, shuffling cards etc
- 盲法
- Participant and Investigator Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 40.00 Year(s)（—）
- 性别
- Female
入选标准
- 未提供
排除标准
- •â€¢ASA III/IV/V •Patients with comorbidites during pregnancy- gestational diabetes mellitus, pregnancy induce hypertension, heart disease •Contraindications of spinal anaesthesia- raised intracranial pressure, local infection, coagulation disorders.
结局指标
主要结局
•post Operative regain of sensory block and motor block
时间窗: Observation of motor and sensory block after spinal anaesthesia in lower segment caesarean section every 5 minutes upto 10 minutes then every 10 minutes upto end of surgery
•post operative duration of first rescue analgesia demand
时间窗: Observation of motor and sensory block after spinal anaesthesia in lower segment caesarean section every 5 minutes upto 10 minutes then every 10 minutes upto end of surgery
次要结局
- Hemodynamic stability after giving spinal anaesthesia in lower segment caesarean section(Heart rate, systolic blood pressure, diastolic blood pressure, respiratory rate, oxygen saturation for every 5 min for 10 minutes then every 10 minutes upto end of surgery)