Different Bispectral Index Guided Remimazolam Total Intravenous Anesthesia-flumazenil Antagonism in Short-duration Ear Nose Throat Surgeries: A Retrospective Cohort Study
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 511
- 试验地点
- 1
- 主要终点
- Incidence of intraoperative awareness
研究概览
简要总结
This study plans to categorize patients who underwent short-duration ENT surgeries with remimazolam TIVA combined with flumazenil antagonism based on whether their intraoperative BIS values were maintained below 60.
详细描述
This study plans to categorize patients who underwent short-duration ENT surgeries with remimazolam TIVA combined with flumazenil antagonism into two groups based on whether their intraoperative BIS values were maintained below 60. It aims to compare the differences in postoperative recovery quality between the groups, thereby providing evidence-based support for determining the optimal BIS target range during remimazolam TIVA.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age 18-65 years
- •ASA I-III
- •Underwent short-duration ENT surgery
- •Underwent remimazolam TIVA combined with flumazenil antagonism.
- •Continuous intraoperative BIS monitoring
排除标准
- •Comorbid severe underlying diseases
- •Intraoperative BIS data were missing or incompletely recorded
- •Severe lack of medical records
研究组 & 干预措施
AB group
Intraoperative BIS values ≤60
HB group
Intraoperative BIS values >60
结局指标
主要结局
Incidence of intraoperative awareness
时间窗: 2hours
Modified Brice Interview From the start of surgery to the end of surgery
次要结局
- Incidence of secondary sedation(1 day)
- heart rate(2 hours)
- usage of vasoactive drugs(2 hours)
- Drug doses(2 hours)
- Awakening time(1 hours)
- PACU stay(1 hours)
- mean arterial pressure(2 hours)