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临床试验/NCT06235359
NCT06235359尚未招募不适用

Is Intercostal Tube Enough in Management of Empyema

Assiut University0 个研究点目标入组 100 人开始时间: 2024年3月最近更新:
适应症

试验速览

阶段
不适用
状态
尚未招募
入组人数
100
主要终点
To find best way to drain the pus in the pleural space

研究概览

简要总结

Is intercostal tube enough in management of empyema ?

详细描述

Empyema refers to presence of pus in the pleural space -Causes Primary: bacterial Pneumonia (staph aureus, strept pneumonia , H.influenza) , TB

Secondry :

PostTraumati postoperative :open heart , esophageal, mediastinum , lung rupture of lung absess

-pathophysiology and stages During an inflammatory process such as pneumonia, there is an increase in fluid production in the pleural cavity known as the exudate stage. As the disease progresses microorganisms, usually bacteria, can colonize the fluid and generated an empyema. This fluid is characterized by elevated lactate dehydrogenase, proteins, neutrophils, and dead cells. Macroscopically is a thick opaque fluid found in the fibrinopurulent stage. After the resolution of the infection and as a consequence of the inflammation, there is a process of fibrosis that can lead to restriction of the lung parenchyma which is stage of chronic organization

研究设计

研究类型
Interventional
分配方式
Na
干预模型
Single Group
主要目的
Treatment
盲法
None

入排标准

性别
All
接受健康志愿者

入选标准

  • patients admitted to Assuit university Hospital and diagnosed with empyema

排除标准

  • Patient diagnosed with Post-operative empyema
  • Patient diagnosed with post traumatic empyema
  • Patient diagnosed with Bronchopleural fistula
  • Patient diagnosed with TB

结局指标

主要结局

To find best way to drain the pus in the pleural space

时间窗: baseline

To find best way to drain the pus in the pleural space

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Islam Abdelfatah mahmoud

physician

Assiut University

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