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临床试验/NCT03796949
NCT03796949已完成不适用

Threatened Preterm Birth and Time of Subsequent Delivery; Prediction Model Based on Biomarkers and Maternal/Obstetrical Characteristics

Linkoeping University0 个研究点目标入组 204 人开始时间: 2014年5月最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
204
主要终点
Time of delivery

研究概览

简要总结

This study investigates immunological and clinical markers in threatened preterm birth aiming to create a prediction model for preterm birth.

详细描述

Preterm birth is the main cause of neonatal mortality and morbidity and despite a lot of effort the mechanisms leading to preterm birth are poorly understood. In threatened preterm birth it is difficult to identify the true high risk cases ultimately leading to preterm birth. These women are often overtreated.

In this study blood samples are taken from women with threatened preterm birth and from women with normal pregnancies before and during labor.

Differences in clinical characteristics and immunological markers between the groups are studied in order to design a prediction model for preterm birth.

研究设计

研究类型
Observational
观察模型
Case Control
时间视角
Prospective

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
Female
接受健康志愿者

入选标准

  • Threatened preterm birth before 34 weeks of gestation; either threatened preterm labor and/or preterm prelabor rupture of the membranes
  • Age > 18 years
  • Swedish-speaking (understanding study information)

排除标准

  • Multiple gestation
  • Blood borne infections

结局指标

主要结局

Time of delivery

时间窗: Outcome noted at delivery

Delivery before 34 weeks of gestation or after 34 weeks of gestation

次要结局

未报告次要终点

研究者

发起方
Linkoeping University
申办方类型
Other Gov
责任方
Principal Investigator
主要研究者

Marie Blomberg

Professor

Linkoeping University

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