Role of Conservative Management in Adhesive Intestinal Obstruction Versus Operative Management
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 50
- 试验地点
- 1
- 主要终点
- X-Ray Changes
研究概览
简要总结
This study aims to evaluate the role of Conservative management in patients with adhesive Intestinal Obstruction Regarding the selection criteria of the patients, duration of conservative route, success rate, and recurrence of adhesions and avoiding the surgical route complications.
详细描述
Adhesive Intestinal Obstruction is very common and represents a serious life threatening condition, which can be caused by congenital band, following abdominal surgeries and other medical conditions like tuberculosis.
The management options for adhesive intestinal obstruction (AIO) could be operative treatment (open-laparoscopy) or non-operative (conservative management) according to many reasons.
Some reports indicate that the operative management for adhesive Intestinal obstruction lead to further adhesions in the future in addition to other possible complications (anaesthetic - iatrogenic injury during adhesolysis - wound site infections - illius-long hospital stay).
The Conservative route is recommended in all patients except those with signs of peritonitis, strangulation, or bowel ischemia which would have been diagnosed during physical examination and imaging.
A few studies compared the advantages, safety, and less complications of Conservative versus operative management. Therefore, this study will be conducted on patients with adhesive Intestinal Obstruction to compare the effectiveness of Conservative versus operative management regarding the selection criteria for the patients, the duration of the Conservative route, things to be done and what need to be observed during the conversation time.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 6 Years 至 70 Years（Child, Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age 6-70 years.
- •Both sexes.
- •Complete \ Partial adhesive Intestinal Obstruction, with CT Abdomen and pelvis with oral and IV Contrast.
排除标准
- •Patients with signs of Strangulation
- •Patients with signs of peritonitis.
- •Patients with signs of bowel ischemia
- •Failure of Conservative management for more than 72 hours.
- •Vitally unstable patients
- •Patients with comorbidities which need rapid interventions.
结局指标
主要结局
X-Ray Changes
时间窗: 72 Hours
Daily Chest Abdomen X-ray Erect copies to evaluate the improvement of the Intestinal Obstruction through evaluation of the X-ray findings (Air fluid levels).
Passability Status
时间窗: 72 Hours
Daily history taking records and per rectal examination findings to evaluate the passability status (stool /flatus)
Hospital Stay Duration
时间窗: from 3 to 5 days.
The Conservative management in patients with adhesive Intestinal Obstruction will avoid them the surgical route which requires long hospital stay postoperative
Vomiting
时间窗: 72 Hours
Frequency and severity of vomiting will be collected to help in prognosis prediction
Abdominal Signs
时间窗: 72 Hours
Data collected about Daily abdominal examination findings (Distention, Intestinal sounds, abdominal pain and Per rectal examination).
次要结局
- Recurrence of Attacks(two years previous the onset of the current attack. (During the last two years before the admission))
- Past Surgical History(two years previous the onset of the current attack. (During the last two years before the admission))
研究者
Osama Khaled Ahmed
Principal investigator
Sohag University