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临床试验/NCT05738928
NCT05738928尚未招募不适用

Microbiological Profile of Ventilator Associated Pneumonia in Respiratory Intensive Care Unit of Assiut University Hospital

Assiut University0 个研究点目标入组 86 人开始时间: 2023年2月最近更新:
适应症

试验速览

阶段
不适用
状态
尚未招募
入组人数
86
主要终点
Microbiological profile of ventilator associated pneumonia in Respiratory ICU in Assiut University Hospital.

研究概览

简要总结

Identification of the microbial profile of Ventilator associated pneumonia causing microorganisms among Respiratory ICU patients .

详细描述

Ventilator-associated pneumonia (VAP) is one of the common serious infectious diseases encountered in the intensive care unit (ICU), which highly affects the healthcare cost and patient prognosis.

All-cause of mortality associated with VAP has been reported to range from 20% to 50%.

The etiology of VAP and their antimicrobial susceptibility pattern varies with different patient populations and types of ICUs.

VAP may be caused by a wide spectrum of bacterial pathogens, which may be polymicrobial and are rarely due to viral or fungal pathogens in immune-competent hosts.

Common etiologic agents are Gram-negative bacilli such as Pseudomonas aeruginosa, Escherichia coli, Klebsiella pneumoniae, and Acinetobacter spp. and Staphylococcus aureus among Gram-positive cocci.

研究设计

研究类型
Observational
观察模型
Case Only
时间视角
Prospective

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Mechanically ventilated patient who developed pneumonia after48 hours after endotracheal intubation.
  • Age > 18 years.

排除标准

  • Patients with clinical and radiological signs suggestive of pneumonia before intubation (community acquired pneumonia or hospital acquired pneumonia)
  • Patients age ≤18 years old

结局指标

主要结局

Microbiological profile of ventilator associated pneumonia in Respiratory ICU in Assiut University Hospital.

时间窗: 1 year

Identify the microbial profile of VAP causing microorganisms among ICU patients, antimicrobial susceptibility patterns among the frequently isolated organisms and resistant strains.

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Manar Abdelhameed Hassan Ali

Doctor

Assiut University

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