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临床试验/NCT03404271
NCT03404271已完成不适用

Time-Restricted Feeding Plus Resistance Training in Active Females: Effects on Body Composition, Muscular Performance and Physiological Variables

Texas Tech University2 个研究点 分布在 1 个国家目标入组 40 人开始时间: 2018年1月17日最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
已完成
入组人数
40
试验地点
2
主要终点
Body fat percentage

研究概览

简要总结

The objective of this study is to examine the effects of time-restricted feeding (TRF; consuming all calories within an 8-hour period of time each day) and resistance training, with or without the addition of the dietary supplement HMB, on body composition, muscular performance and physiological outcomes in active females.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Factorial
主要目的
Other
盲法
Triple (Participant, Investigator, Outcomes Assessor)

盲法说明

Investigators and participants will be blinded to dietary supplement (i.e. HMB or placebo). However, neither the investigators nor participants will be blinded to dietary intervention (TRF or ND) due to the nature of these dietary programs. When possible, outcome assessors will be blinded to group assignment.

入排标准

年龄范围
18 Years 至 30 Years(Adult)
性别
Female
接受健康志愿者

入选标准

  • Female between 18 and 30 years of age
  • Current university affiliation
  • Weighing at least 110 pounds
  • Generally healthy
  • Resistance-trained
  • Schedule availability to complete supervised resistance training
  • Body fat percentage between 15 and 29%

排除标准

  • Pregnant or trying to become pregnant
  • Currently breastfeeding
  • Any disease, condition or orthopedic limitation that would prevent safe participation in resistance training or time-restricted feeding
  • Current smoker
  • Presence of pacemaker or other electrical implant
  • Allergic to dairy proteins

研究组 & 干预措施

Normal Diet

Placebo Comparator

Participants in the normal diet (ND) group will follow a traditional dietary pattern, consisting of eating breakfast and continuing to eat throughout the day until the evening. Participants in this group will receive placebo capsules. Participants in all groups will follow an identical resistance training program and be provided with whey protein supplements.

干预措施: Resistance Training (Other)

Normal Diet

Placebo Comparator

Participants in the normal diet (ND) group will follow a traditional dietary pattern, consisting of eating breakfast and continuing to eat throughout the day until the evening. Participants in this group will receive placebo capsules. Participants in all groups will follow an identical resistance training program and be provided with whey protein supplements.

干预措施: Protein Supplementation (Dietary Supplement)

Time-Restricted Feeding

Experimental

Participants in the time-restricted feeding (TRF) group will consume all calories within an 8-hour period of time each day. Participants in this group will receive placebo capsules. Participants in all groups will follow an identical resistance training program and be provided with whey protein supplements.

干预措施: Resistance Training (Other)

Time-Restricted Feeding

Experimental

Participants in the time-restricted feeding (TRF) group will consume all calories within an 8-hour period of time each day. Participants in this group will receive placebo capsules. Participants in all groups will follow an identical resistance training program and be provided with whey protein supplements.

干预措施: Protein Supplementation (Dietary Supplement)

Time-Restricted Feeding

Experimental

Participants in the time-restricted feeding (TRF) group will consume all calories within an 8-hour period of time each day. Participants in this group will receive placebo capsules. Participants in all groups will follow an identical resistance training program and be provided with whey protein supplements.

干预措施: Time-Restricted Feeding (Behavioral)

Time-Restricted Feeding plus HMB

Experimental

Participants in the time-restricted feeding plus HMB (TRF+HMB) group will consume all calories within an 8-hour period of time each day. Participants in this group will receive HMB capsules. Participants in all groups will follow an identical resistance training program and be provided with whey protein supplements.

干预措施: Beta-hydroxy beta-methylbutyrate (Dietary Supplement)

Time-Restricted Feeding plus HMB

Experimental

Participants in the time-restricted feeding plus HMB (TRF+HMB) group will consume all calories within an 8-hour period of time each day. Participants in this group will receive HMB capsules. Participants in all groups will follow an identical resistance training program and be provided with whey protein supplements.

干预措施: Resistance Training (Other)

Time-Restricted Feeding plus HMB

Experimental

Participants in the time-restricted feeding plus HMB (TRF+HMB) group will consume all calories within an 8-hour period of time each day. Participants in this group will receive HMB capsules. Participants in all groups will follow an identical resistance training program and be provided with whey protein supplements.

干预措施: Protein Supplementation (Dietary Supplement)

Time-Restricted Feeding plus HMB

Experimental

Participants in the time-restricted feeding plus HMB (TRF+HMB) group will consume all calories within an 8-hour period of time each day. Participants in this group will receive HMB capsules. Participants in all groups will follow an identical resistance training program and be provided with whey protein supplements.

干预措施: Time-Restricted Feeding (Behavioral)

结局指标

主要结局

Body fat percentage

时间窗: 8 weeks

Assessed using multi-compartment model

Upper body muscle hypertrophy

时间窗: 8 weeks

Muscle thickness of elbow flexor muscles

Lower body muscle hypertrophy

时间窗: 8 weeks

Muscle thickness of knee extensor muscles

Fat mass

时间窗: 8 weeks

Assessed using multi-compartment model

Fat-free mass

时间窗: 8 weeks

Assessed using multi-compartment model

次要结局

  • Blood C-reactive protein(8 weeks)
  • Upper body muscular endurance(8 weeks)
  • Cortisol awakening response(8 weeks)
  • Lipid panel(8 weeks)
  • Blood glucose(8 weeks)
  • Blood insulin(8 weeks)
  • Mood(8 weeks)
  • Physical activity level(8 weeks)
  • Lower body muscular strength(8 weeks)
  • Lower body muscular endurance(8 weeks)
  • Upper body muscular strength(8 weeks)
  • Sleep quality(8 weeks)
  • Lower body muscular power characteristics(8 weeks)
  • Blood pressure(8 weeks)
  • Respiratory quotient(8 weeks)
  • Eating behavior(8 weeks)
  • Arterial compliance(8 weeks)
  • Resting metabolic rate(8 weeks)

研究者

申办方类型
Other
责任方
Sponsor

研究点 (2)

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