JPRN-jRCTs031190150已完成未知
The relationship of AMPA receptor density in patients with depression and bipolar disorder :a transversal PET study using [11C]K-2
Miyazaki Tomoyuki0 个研究点目标入组 60 人开始时间: 2019年12月2日最近更新:
适应症
试验速览
- 阶段
- 未知
- 状态
- 已完成
- 发起方
- 入组人数
- 60
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- >= 20age old 至 < 60age old（—）
- 性别
- All
入选标准
- •We will target someone who meets all the following conditions.
- •1. Psychiatric Diagnostic Interview Manual (Structured Clinical Interview for DSM-IV, SCID-I / DSM-IV), Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM 5), and International Disease Classification 10th Edition (International Statistical Classification) of Diseases and Related Health Problems 10th Revison, ICD-10) that meet the criteria for depression or bipolar disorder
- •2. Men and women between 20 and 60 years old at registration
- •3. Patients who have given written consent to participate in this study.
- •4. Cases in which the person's consent judgment ability is judged to be sufficient by the evaluation by the MacArthur Competence Assessment Tool (MacCAT)
排除标准
- •It will be excluded if any of the following conditions apply.
- •1 During pregnancy, nursing or wishing to be pregnant(For premenopausal women,blood hCG is measured by blood sampling and confirmed to be less than 6 mIU / ml)
- •2 Sensitive to alcohol
- •3 Combination of serious neurologic diseases (neurodegenerative diseases, cases of cerebral hemorrhage and cerebral infarction which are not slight in the image before this study participation)
- •4 History of epilepsy
- •5 Take Perranpanel, Topiramate within 4 weeks before registration
- •6 Substance-related disorders within 6 months (except for nicotine and caffeine)
- •7 Dependent substances positive by urine screening (except those who are positive for the medicine being taken for treatment)
- •8 Implantation of metal substances and pacemakers
- •9 head, neck and body size not suitable for MRI scanner
- •10 A tattoo larger than one point (including tattoo and art makeup)
- •11 Advanced claustrophobic
- •12 A remarkable variant of brain structure (including congenital and traumatic)
- •13 At the time of registration, any of the following laboratory test value abnormalities
- •Serum creatinine 1.5 mg / dl or more
- •AST 150 IU / L or more
- •ALT 150 IU / L or more
- •14 Participating in unapproved nuclear medicine clinical trials and clinical trials within 6 months prior to enrollment
- •15 Participating in other trials or clinical trials within 12 weeks prior to enrollment (limited to those with invasiveness / intervention)
- •16 Patients judged as inappropriate for study by the research investigator
研究者
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