Intrinsic Indigestible Carbohydrates as Means to Modulate Colonic Events, With Specific Focus on Metabolism and Satiety
试验速览
- 阶段
- 早期 1 期
- 状态
- 已完成
- 入组人数
- 19
- 试验地点
- 2
- 主要终点
- Insulin
研究概览
简要总结
The experimental model is a semi-acute study where the purpose of the study is to evaluate food factors related to colonially derived regulation of glucose metabolism (and related parameters) and satiety in healthy subjects.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Prevention
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 20 Years 至 35 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Normal fasting blood glucose, BMI 19-25 kg/m2
排除标准
- •Gastrointestinal diseases or food allergies e.g. lactose-, gluten intolerance, metabolic disorders e.g. diabetes, tobacco/snuff users. Antibiotic or probiotic usage within two weeks, and during study. Vegetarians.
结局指标
主要结局
Insulin
时间窗: Postprandial 0-180 min after breakfast
The test products are both ingested one day and three days prior to measurements of variables.
Markers of colonic fermentation and inflammation
时间窗: Postprandial 0-180 min after breakfast
The test products are both ingested one day and three days prior to measurements of variables.
Blood glucose
时间窗: Postprandial 0-180 min after breakfast
The test products are both ingested one day and three days prior to measurements of variables.
Appetite hormones
时间窗: Postprandial 0-180 min after breakfast
The test products are both ingested one day and three days prior to measurements of variables.
次要结局
- Subjective satiety(Postprandial 0-180 min after breakfast)
研究者
Jonna Sandberg
MSc, postgraduate student
Lund University