NCT01698944终止4 期
Cardiovascular Effects on Growth Hormone Replacement Therapy in Adults With Primary or Secondary Childhood Onset Growth Hormone Deficiency
适应症
干预措施
相关药物
试验速览
- 阶段
- 4 期
- 状态
- 终止
- 入组人数
- 7
- 试验地点
- 1
- 主要终点
- Left Ventricular systolic function
研究概览
简要总结
This trial is conducted in Europe. The aim of this trial is to investigate the effect of growth hormone on left ventricle morphology and function (systolic and diastolic).
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 12 Years 至 25 Years（Child, Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Adult growth hormone deficiency
- •At least 2 years without growth hormone treatment
排除标准
- •Supine blood pressure above 160 mmHg systolic or above 100 mmHg diastolic
- •Pregnancy
研究组 & 干预措施
Somatropin
Experimental
干预措施: somatropin (Drug)
结局指标
主要结局
Left Ventricular systolic function
Left Ventricular diastolic function
次要结局
- Body composition
- Oral glucose tolerance test (OGTT)
- Fasting glucose
- HbA1c (glycosylated haemoglobin)
研究者
研究点 (1)
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