Is Acupuncture Able to Reduce Nausea and Vomiting in the Terminal Ill Patient
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 136
- 主要终点
- Change in vomiting
研究概览
简要总结
A comparative effectiveness research design was used. The sample size was calculated to 136 patients, who were randomized to an intervention group and a control group respectively. The patients were terminal ill patients enrolled to three in-bed hospices in Denmark and nausea and vomiting were measured using EORTC QlQ-c15-PAL (European Organisation for Research and Treatment of Cancer, Quality of Life Questionaire, core 15, Palliation)
详细描述
The terminal ill patient is suffering from many different symptoms. In total 70% are suffering from nausea and vomiting due to the wide spread of cancer or due to side effects of treatment. Often the antiemetic's are not able to reduce symptoms to a level that enable the patient to experience quality in life in the last days of his life. The investigators had some experience with acupuncture as a complementary therapy but the investigators wanted more systematically to investigate if acupuncture is able to reduce the terminal ill patient´s nausea and vomiting. Literature show that acupuncture is able to reduce nausea and vomiting in patients receiving chemotherapy, but there is no literature that support the ability of acupuncture to reduce nausea and vomiting in the terminal ill patient.
The purpose of this study was to generate evidence based knowledge close to practice regarding the effect of acupuncture in reducing nausea and vomiting in the terminal ill patient.
Participants:
Terminal ill patients suffering from nausea and/or vomiting
Interventions:
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Able to participate due to cognitive ability
- •Admitted to in-bed hospice
排除标准
- •Not able to participate due to cognitive impairment
- •Lymphedema in the area of acupuncture site
结局指标
主要结局
Change in vomiting
时间窗: Change in vomiting from before intervention to four day after the intervention
Unit of measure: Incidence of vomiting using the outcome measure question: Yes or No
Change in nausea score
时间窗: Change in nausea score from before intervention to three day after the intervention
Using EORTC QLQ-c15-PAL, the nausea item. Values: not at all, a little, quite a bit, very much. Very much is the worse outcome
次要结局
未报告次要终点